Jim, provided that your NuC and your Qutest are in the same location, all that is required is a USB cable. I have this setup in my office and it sounds fantastic, the Chord Qutest really rocks! A purist will suggest that you may get electrical noise from the NuC, while my setup sounded great, I purchased a fanless case from Akasa. Was a fun project to breakdown the Nuc and install into the case, brought some improvement in sound which already rocked hard!