No, it still applies since the desktop is simply presenting audio settings (I should have said GNOME, but any DE will have audio settings.)
If you use the audio interface as the default audio output, any app on the machine can take exclusive control of the device. To avoid this use the default audio output, which uses the OS mixer.
It may be helpful to understand your use case, and how you are using the audio interface.
So as long as I don’t try to start music in Roon too quickly after listening to another source (e.g. YouTube), then Roon is happy. However, I’m still experiencing an issue in the other direction: once Roon has grabbed the audio output device, it will not let it go until I reboot my computer.