I had a similar problem, that I thought was being caused by Roon, but had an interesting discussion with Danny as to why this wasn’t the case. To sum up Danny’s point, Roon shouldn’t be able to cause a kernel panic. Sure, it can fail in its own right, but it shouldn’t be able to bring down the whole OS too. In the thread I just linked I initially thought that the problem might be to do with various kexts installed on my machine, but in the end it turned out to be a problem with a USB hub. Specifically, one hub piggy-backed off another. My solution was to replace the hub with a powered version and I haven’t had a single panic since.
tl;dr - it might be worth taking a look at the peripherals you have attached to the mini with a view to ruling them out as a cause.