As I understand @AMP’s question/report, it’s not about any one music format. The thing he’s saying provokes the problem is transitions between different music formats on the same playlist. So, for example, playing two 44.1/16 MP3 files and then a 96/24 FLAC file would be more likely to cause a stop at the 44.1/16 -> 96/24 transition.
In addition to his evidence that this is a problem, Roon internally effectively stops and restarts the whole stream to change DSP settings when this occurs. This gives a mechanism as to why this would be more likely to cause breakage in the Sonos streaming mechanism, because there are more moving parts to go wrong.
(Sadly, I’ve tried looping playlists of 5second tracks each with a different format, and can’t trigger this reliably)