Thanks for giving the proposed test a shot, @Martin_Joyce. Sorry to hear that it did not yield a more positive result.
Moving forward, may I very kindly ask you to please provide the following information to help in in my evaluation of this behavior. Please see below.
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Please expand on the description of your current setup, using this link as a guide.
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In regard to your network configuration, are there any other devices in play besides the Asus router (i.e switches, repeaters, extenders, etc)? If there are indeed, can you please describe where they are sitting in the chain of communication.
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Just to verify, rebooting your core does not remedy this behavior, correct?
-Eric