The power supply was the problem. I originally had the screen taking power for the Pi’s GPIO pins.
Using a separate power supply for the screen solved the problem.
@mvrlogins That shouldn’t be a problem, as long as your power supply delivers enough current.
I am using RPI3B+ with 1st gen display connected via the GPIO pins. The powser supply is 5V 4A (= 20W). But using a separate power supply for the display is also a good solution.
Kind regards, Frank.