Based on your account admin, it looks like you’re running Roon Server on a macmini, is this correct?
If so, I’d first reboot your Mac mini, and ensure Roon Server is on and running (you can see the Roon jellyfish via your macOS taskbar.)
Do you run into this issue no matter the remote app you use? I see you have Roon mobile on an ipad, if you remove the Roon mobile app and perform a fresh install, are you able to connect?
Wanted to follow up on this. Were you able to reboot your Mac mini and confirm that Roon Server is still running, with the jellyfish showing in the macOS menu bar? We also asked whether the issue happens with every remote app, and whether a fresh reinstall of the Roon mobile app on your iPad changes anything. If you have a moment, let us know what you found and we can take it from there.
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