Danny posted this some time back, WRT Trim mainly but his comment is implying writes are kept to a minimum on the Boot Drives for Rock/Nucleus
Why there seems to be a rather high failure rate on Nucleus would perhaps appear to be something to do with the source/manufacturer for these units of the m.2 SATA component (not NVMe that I am aware of) so this is something Roon needs to chime in on.