Difference is that most Atom/Celeron/Pentium branded CPUs (all based on Atom core) have only SSE4.2 and lack AVX2 which would be over 2x as powerful for same clock rate. In very latest Atoms Intel introduced AVX2 to Atom also, since the core is same one that have already been in 12th and 13th Gen Core as Efficiency Cores.
Regular Fedora build is AVX2-only, with CUDA support. Then there’s the SSE4.2 build that doesn’t have CUDA support, it is for small Atom/Celeron/Pentium-based devices.
Regular Ubuntu build is SSE4.2/AVX/AVX2/AVX-512 with CUDA support. And then there’s AVX2-only build for Ubuntu as well, which is usually best option for all recent bigger Intel/AMD CPUs.
Debian build is mostly SSE4.2 with limited AVX/AVX2/AVX-512 support and also includes CUDA support. It thus works on wide variety of hardware, but is usually not quite as fast as the AVX2-only builds on Fedora and Ubuntu.
Set DAC Bits to Default. And Default Output Mode to PCM.
Otherwise your settings are probably fine. You can experiment with different filters and noise-shapers/dithers. There’s some guidance provided in the manual that can hopefully help in trying to find settings that best match your use cases.