I just got a Nucleus and I have a legacy equipment not Roon Ready and I am not sure how to get the best audio from them

Yes, you could do that. Whether or not you get a superior sound is another matter, depending on a lot of things.

I use USB to a Topping D70 DAC which goes straight into my power amp, for instance. I use the analog side of the DAC as a preamp.

There is an issue with digitally controlled preamps. Bad code or resets or bugs might cause them to turn on with full volume and ruin your speakers. Many recommend putting a passive preamp in between the DAC and the power amp. See this thread:

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