@Martin_Webster Just tried it. It said “This device is not compatible with Roon 2.0” during setup 
@abbluiz, I’ve moved your last post to a new thread, as the discussion is moving off-topic.
If you’d like some assistance from the community, please provide some information about the distro you’re using and what you have tried so far.
Distro: Fedora 36
I installed wine and winetricks from the default repositories of my distro and then
I simply went to GitHub - RoPieee/roon-on-wine: Running Roon with Wine on Linux and tried to run the script.
It stops in a window “This device is not compatible with Roon 2.0”
Nevermind. There’s a fix for that, explained in Can't install Roon 2.0 · Issue #26 · RoPieee/roon-on-wine · GitHub
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The minimum requirements for Roon 2.0 have changed: Windows 10 and 64-bit only.
Roon GUI runs without problems on Ubuntu and Fedora using Crossover from Codeweavers. I had to install the Microsoft.NET framework 4.6.2 in the bottle to get it to work. I haven’t tried setting it up using Wine directly.
Anyone knows how to install Roon on NixOS?
Give Roon on Wine a try, or install manually.
Note the dependencies, and that you’ll need Wine staging.