Lossless or converted and rendered hi rez?

Core Machine (Operating system/System info/Roon build number)
Windows 10

Network Details (Including networking gear model/manufacturer and if on WiFi/Ethernet)

Audio Devices (Specify what device you’re using and its connection type - USB/HDMI/etc.)
NAD D3045 USB

Description Of Issue
I’m not sure which format (Hi rez, MQA or lossless) will give best quality.

I could give you a generalisation… but really it depends on the track, how it was mastered (and / or encoded).

Where you have choice let your ears decide …

I think you have already answered your own question…