I don’t think there is a pre-built integration.
My usual fallback is to see if it’s possible to go via Home Assistant (I maintain the roon integration) - but there doesn’t look to be an easy Loxone / Home Assistant integration.
So my thoughts are are:-
- You could write something using the roon API (if you’re a developer)
- Make use of of the http integration (there is a post here that indicates someone has this working with Loxone): Roon extension - http APIs - #146 by many
- If you can run a command line programme from Loxone - you could use the roon command line interface Roon extension - http APIs - #146 by many
Please note that 2 & 3 are user supported software.