Maybe, probably, all of you know this, but just in case someone don´t, I want to share my experience in my main system with two graphic cards and a 4K display.
When I installed Roon in it, W10, the AMD Radeon was assigned automatically to manage Roon interface graphics. That meant more heat and, consecuently, the fan began to “be there”, I mean noisy enough to disturb while listening music. So, I decided to manually choose the intel graphic card to take care, instead of the AMD card, of Roon Interface. It works perfectly smooth, just like with the AMD, but now the computer´s fan keeps been very, very quiet.
Salud.