Hi @kjwho ---- Touching base with you to confirm what graphics card is being used in the Asus desktop? As Peter pointed out in his post, we have seen issues tied to the Intel HD 4000 GPU with one of Windows’ most recent updates.
If you are indeed using an Intel HD 4000 graphics card, the work around currently (as reported by other users) are to either A) roll back to a previous update or B) Try using the 32 bit version of Roon as TopQuark points out above.
-Eric