Connecting to DACs long distances across the house

I use a Mac Mini M-1 as my Roon Core. I connect to a group of Airplay devices around house for casual listening. I use. Mytec Brooklyn Bridge+ via USB in my main room. I would like to connect to two high quality DACs in studio and master bed. One will barely connect via a 25 ft USB cable. The other is a 80+ ft run and I am looking for suggestions better than Airplay? Considering USB via fiber optic, wired Ethernet? Suggestions, pros and cons with a focus on quality high res PCM and DSD?

Sounds like you really need remote endpoints near each of these like a Pi or a Wiim.
These connected by Ethernet then USB out to the pair of dacs.

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I moved your thread to Audio Gear Talk so you should receive a few more useful replies than being in Uncategorized.

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Assuming you already have the DACs, then some sort of Roon Ready streamer to connect to your network via ethernet then USB to your DAC is probably the best option. There are lots of choices at all sorts of price points - as @AceRimmer suggested there are good inexpensive options, or you can go higher up the food chain with the likes of Cambridge Audio, Chord, Auralic, Lumin, etc. If you don’t already have the DACs, then there are a lot of good streaming/DACs out there.

There’s a fairly recent thread here:

iFi Zen Stream via Ethernet is a fairly affordable option. Spdif or usb output.