Some types of Roon Core devices will give you more than one Zone that nevertheless plays to the same hardware. For example, a Windows machine that may give you both “System Output” and another Zone such as “Intel Wasapi”. In that case, you might be able to set up one of the Zones for DSD, without any DSP enabled.
I did something like this for a while. You still have to switch to that Zone when playing DSD, but I found it simpler than going into DSP settings. But I usually pick an entire album to play – I imagine it would be tedious to keep switching Zones on a track-by-track basis.