Thanks for your suggestions. I appreciate them!
Mine is May KTE. I think I’ve isolated the DAC enough when investigating the cause, but I’ll do it more thoroughly. 
I kinda have a preference for using unbalanced connection due to a suggestion from a late, acclaimed critic in Japan. Tetsuo Nagaoka was an Accuphase user, but he didn’t use balanced connection.
Well, that’s quite in the past, so perhaps I should start using some more.
Also, C-2800 is an unbalanced-circuit preamplifier, so aside from addressing the noise issue, SQ will not improve with balanced connection.
If you’re curious, use Google Translate to see who he was.
Well, for some reason, the gain changes the sound profile, so that’s a trade-off.
I played with later models at an audio shop and kept the overall gain the same (e.g., setting the preamp at +24 and the power amp at +12, then reversing the gain values on both amps).
Somehow, the sound profile changed so much that I don’t trust the quality of the gain control function on Accuphase amplifiers. In fact, they seem to be controlled with small resistors, one for each gain value.
I’m aware of that. I keep the I2S in case I want to use two outputs from the RED (i.e. I2S and SPDIF coaxial that goes to an AV preamp) to play the same music source simultaneously. When I use the USB input, the other outputs from RED don’t work for some reason. (Perhaps due to UAC 2 Gen 2.1) But anyway, I rarely use I2S these days.
Good to know this. I somehow use a flat-looking cable (simply because it looks nice), and I doubt it has twisted-pair conductors. I’ll change it to a better one.
Accuphase didn’t have the function to preserve polarity, including the C-2800 I use. Some newer models do. So, it would be inconvenient if you use multiple sources – you’ll have to change the polarity every time you switch sources.
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Although it seems “okay” for now, I’ll see what I can do to reduce more of the hum.
Thanks again, everyone! 