First off is the node 2 your only endpoint in your setup? If so ensure that the device running the remote app is on the same network and subnet as your Roon core and the Bluesound.
An easy check is to check each devices IP address they should have the same identical first 3 numbers and a unique 4th.
You seem to have two routers by your post so likely you are running two DHCP servers and they are running on different networks this seems the likely problem. Roon does not traverse different networks. You should only have one router in a network controlling DHCP.