I’m having the same issue with Qobuz not playing through Roon, even though Tidal plays fine.
My Core is on a Zuma build with an Intel I3, running Win10. It goes from there to a Bryston BDA-2 DAC and on to a McIntosh MA6600. I control Roon using an iPad Air.
My Network is Comcast that typically gets 150+ MB according to SpeedTest. The modem is connected to an Airport Extreme and extended to an Airport Express, where SpeedTest clocks it at between 30-50 MB. The Zuma Win10 is connected to the Express via a gig switch.
My local content is stored on a Synology NAS, hooked to a gig switch that is connected to the Airport Extreme. I have no trouble with HD content up to 24/196.