Hi @Stephen_Harris,
Please see our documentation on this at the following link:
Use SMBv3 when possible. Failing that, SMBv2 should also be ok, but do not use smb2 with large MTU as it has known compatibility issues with Roon. If you’re using a Synology NAS and running your Roon Core on macOS, you can find some more information about fine-tuning your setup here
Don’t enable AFP or Timemachine if possible – some users may need this functionality for other applications, but they’re not needed for Roon. You can find more information about why AFP is not supported here
Hope this helps!